A decade of making medicines accessible
18 billion doses of treatment in 10 years
Annual report 2020
Annual report 2020
MPP licences have generated USD 1.96 billion in global health savings through the procurement of more affordable quality-assured medicines from MPP generic partners through an average price reduction
relative to the originator price
Generic products facilitated by MPP have been distributed in 148 countries providing 49.71 million patient-years of treatment from January 2012 to December 2020MPP’s impact is calculated and verified by KPMG
The University of Liverpool and the University of Washington secure Unitaid grants for long-acting products; MPP proudly partners with both to increase access to these revolutionary technologies.Read more
MPP co-sponsors a conference on long-acting injectables and implantables with MedinCell..Read more
MPP and Viatris (through its subsidiary Mylan) sign an agreement to scale up access to the first generic version of hepatitis C treatment glecaprevir/pibrentasvir.Read more
At WHO’s request, MPP begins to collect patent data on treatments being tested for COVID-19 and adds these to MedsPaL.CHECK MedsPaL
MedinCell secures Unitaid grant for long-acting solution for malaria; MPP will partner on accelerating access.Read more
MPP strongly supports multilateral COVID-19 global response and stands ready to contribute to the Access to COVID-19 Tools Accelerator (ACT-A).Read more
MPP’s statement at the 73rd World Health Assembly welcomes Resolution WHA73.1 that calls to work collaboratively through “existing mechanisms for voluntary pooling and licensing of patents”.Read more
MPP is a co-publisher, along with WHO and seven other leading organisations, of the policy brief ‘Considerations for introducing new antiretroviral drug formulations for children’.Read more
MPP co-organises a satellite symposium at AIDS 2020 (virtual) together with Unitaid and WHO. The panel discusses access to long-acting technologies for HIV in LMICs.Read more
MPP and the International Diabetes Federation join forces to improve access to diabetes medicines.Read more
MPP co-organises a panel at the World Health Summit 2020 (virtual) with Unitaid and WHO; discussion focuses on access to essential medicines in LMICs – a prerequisite to achieving Universal Health Coverage.Read more
Algeria gains inclusion to ViiV Healthcare/MPP adult licence enabling greater access to dolutegravir-based HIV treatments.Read more
MPP showcases the progress and good initiatives taken in Kenya for greater access to medicines through a series of videos and written pieces.Read more
MPP leads an open pledge bringing together generic manufacturers to combine forces for developing and delivering affordable COVID-19 interventions.Read more
MPP participates in the Vatican meeting; keeps “access to child-friendly medicines” high on the agenda.Read more
MPP secures a new USD 34.3 million grant from Unitaid for five years (2021-2025).Read more
ViiV Healthcare and MPP expand access to dolutegravir-based regimens for people living with HIV in Azerbaijan, Belarus, Kazakhstan and Malaysia with an innovative new licensing agreement.Read more
Prof. Mojisola Christianah Adeyeye and Prof. John-Arne Røttingen join MPP’s Governance Board.Read more
MPP sublicenses sutezolid, an investigational drug for TB treatment, to the Gates Medical Research Institute, paving the way for clinical development.Read more
WIPO joins MPP’s Governance Board as a non-voting member.Read more
Since 2010, and the foundation of MPP, much has happened – dozens of negotiations on public health licences, hundreds of partnerships across sectors, billions of doses of treatment supplied through MPP’s licences, and much more. And behind all these successes are hard-earned lessons that we have gathered, one lesson at a time. Each of these 10 precious lessons, as reflected in our partners’ voices, has made our foundation stronger than ever.
Our vision is a world in which people in need in low- and middle-income countries (LMICs) have rapid access to effective and affordable medical treatments and health technologies.
Our mission is to increase access to, and facilitate the development of, life-saving medicines for LMICs through an innovative approach to voluntary licensing and patent pooling. We work with a range of partners — civil society, international organisations, industry, patient groups and governments — to prioritise and license novel and existing medicines and health technologies for people in these countries.
27.4 million people were accessing antiretroviral therapy in 2020, an increase of 2m since 2019
living with HIV still miss out on HIV treatment, of whom the vast majority live in low- and middle-income countries11UNAIDS, 2020 fact sheet (last accessed on 14 June 2021)
Access to hepatitis C treatment is improving but remains too limited.
of those living with the HCV infection knew their diagnosis.
Of those diagnosed with chronic HCV infection, 9.4 million people (62%) had been treated with DAAs by the end of 2019.
Much more needs to be done to achieve80%
HCV treatment target by 20302.2World Health Organization, Global report on HIV, viral hepatitis and sexually transmitted infections, 2021
Multidrug-resistant TB (MDR-TB) remains a public health crisis and a health security threat. A global total of 206,030 people with multidrug- or rifampicin-resistant TB (MDR/RR-TB) were officially diagnosed and notified in 2019, a 10% increase from 2018. Ending the TB epidemic by 2030 is among the health targets of the Sustainable Development Goals (SDGs). To meet this target, faster-acting and better therapies to treat TB are urgently needed, particularly for MDR-TB4.4World Health Organization, Fact Sheet, Tuberculosis, October 2020 (website accessed on 14 June 2021)
COVID-19, the disease that dominated the world’s attention throughout 2020, was declared a pandemic by WHO on 11 March 2020. Shortly after, MPP swiftly realised that equitable access to medicines and technologies for COVID-19, as they become available, will be a key factor in determining how effectively we deal with this pandemic. In consequence, MPP’s Board expanded the organisation’s mandate to COVID-19 on 31 March 2020.
The following days and months saw MPP charting the possible roles it could play in defeating the new coronavirus. By applying its tested voluntary licensing and patent pooling model, MPP could:
Help fulfil the need for huge volumes of treatments through its generic manufacturing partners
Leverage its broad partnerships towards increasing the geographical reach of effective technologies, especially in low- and middle-income countries
Aid in bringing down the prices of medicines by introducing multiple generic players and driving healthy competition among them
Ensure quality of generic versions of licensed health products
Complement direct efforts of originators and public health organisations towards leaving no one behind
Provide a sustainable model that does not rely on a philanthropic approach to access – one-off charities, philanthropic donations etc.
MPP’s mandate is expanded to include COVID-19 treatments and technologies.Read more
WHO calls MPP to join its COVID-19 Technology Access Pool (C-TAP).Read more
MPP becomes part of the Access to COVID-19 Tools Accelerator (ACT-A) therapeutic pillar led by Unitaid and WHO.
Manifesto for EU (European Union) COVID-19 research mentions voluntary pooling and licensing of intellectual property related to COVID-19 therapeutics and vaccines as a key facet.
MPP leads an open pledge with 21 generic manufacturing companies, who commit to working with MPP to fulfil the manufacturing demand for COVID-19 treatments, especially in LMICs.Read more
G20 endorses voluntary licensing of intellectual property for COVID-19 products: “We have mobilised resources to address the immediate financing needs in global health to support the research, development, manufacturing, and distribution of safe and effective COVID-19 diagnostics, therapeutics and vaccines. We will spare no effort to ensure their affordable and equitable access for all people, consistent with members’ commitments to incentivise innovation. In this regard, we fully support all collaborative efforts, especially the ACT-A initiative and its COVAX facility, and the voluntary licensing of intellectual property.”Read more
UN General Assembly annual resolution on “Global health and foreign policy: strengthening health system resilience through affordable health care for all” (document A/75/L.41) encourages the use of existing mechanisms, such as the Medicines Patent Pool, to promote equitable, affordable and timely access to medical products and health technologies in health emergencies."Read more
Initiating exploratory talks with patent holders of essential medicines for non-communicable diseases (NCDs), including cardiometabolic diseases and cancer, to gather industry perspectives and positions on the MPP model and explore potential willingness to partner with MPP to facilitate access to innovative products.
to improve access to affordable and high-quality diabetes medicines in LMICs.
to work closely in furthering the shared goal of promoting wide availability of quality, safe, effective and affordable essential medicines for better cardiovascular health.
this meant, in particular, the addition of biotherapeutics for NCDs that were added to the WHO EML in 20195.
With the World Heart Federation to improve access to NOACs (non-vitamin K antagonist oral anticoagulants) to make these life-saving innovations affordable and available in low-resource settings. The recommendations were published in the peer-reviewed journal Global Heart.
With the inclusion of several biotherapeutics in the WHO EML over the past three revisions, the WHO Expert Committee requested MPP to consider the application of its model to biotherapeutics. In that context, MPP started an assessment that will be concluded in 2021.
Long-acting regimens for the treatment or prevention of chronic illnesses, such as weekly oral pills or monthly patches, injectables and implants, are emerging as game-changers in healthcare. These pioneering innovations offer people a simpler yet effective way of administering medicines that frees them from daily pills, helps them stay on treatment and reduces the burden on health systems.
2020 started as an exploratory phase in the long-acting space for MPP, and by year-end, it became an integral part of MPP’s ongoing work.
MPP partnered with all three of Unitaid-funded long-acting projects – MedinCell, the University of Liverpool and the University of Washington
During the third Long-Acting Injectables and Implantables Conference in La Jolla, California (6-7 February 2020): MPP co-organised the side event with MedinCell to raise awareness about access to health technologies in LMICs.
MPP co-organised with Unitaid and WHO a satellite session titled “Harnessing access to long-acting technologies in low- and middle-income countries: are we on track to resolving the conundrum?”
Bringing its expertise to shaping the long-acting agenda in these areas, for which availability of extended-release drugs and formulations could profoundly affect treatment.
MPP ENGAGED with community representatives, treatment advocates, civil society members, the research and development community and the industry throughout the year to seek their perspectives on the needs and wants related to long-acting technologies and formulations, as well as potential bottlenecks that MPP could help address.
MedsPaL is a free resource that provides information on the intellectual property status of selected patented essential medicines in LMICs.
MedsPaL was launched in October 2016, focusing on medicines for three diseases: HIV, hepatitis C and tuberculosis. In December 2017, it was expanded to cover all patented medicines on the WHO EML. After the new WHO EML was released in July 2019, MedsPaL was updated to include patent information on the 18 newly listed medicines.
2020 brought MPP into the limelight on numerous occasions and in diverse contexts. With COVID-19 on the top of the global health agenda and MPP’s experience and model in access to medicines for other diseases, it was no surprise that a lot of MPP’s media mentions were related to COVID-19. MPP continued to bring even more life-saving treatments and access to HIV and hepatitis C medicines in 2020, and these achievements were newsworthy too! Here is a sample of news coverage on MPP in 2020.
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